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Complete nucleosome disruption occurs at the DSB in asynchronous cells. ChIP of (A) histone H2A, (B) histone H2B, (C) histone H3, (D) histone H4, and (E) RPA32 in MCF7 cells stably expressing ddI-PpoI as described in Fig. 1B cultivated in serum containing 0.1% or 10% FBS for 24 h before DSB induction. *P < 0.05.
