Fig. 2.

Synergy at NKG2A occurs with a broad range of peptides. Degranulation of CD3⁻ CD56⁺ NKG2A⁺ CD158b⁻ NK cells in response to increasing concentrations of the following peptides in the presence (■) or absence (●) of 1 µM HLA-A2_sp: (A) HIV p24_14–22; (B) EBV BZLF_39–47; (C) hsp60_sp; (D) the HLA-E–binding mutant HLA-G_R5K; and (E) the HCV core_R5K mutant (Left) and the control HCVcore_35–44 for this experiment (Right). Data are shown as mean ± SEM of three independent experiments. All P values were calculated using one-way ANOVA.