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. 2013 Oct 21;4:329. doi: 10.3389/fimmu.2013.00329

Figure 2.

Figure 2

(A) Scaled functional sensitivity w as a function of scaled total CD8 density xT for various scaled TCR/pMHCI off-rates α. (B) Degeneracy curves ℙ(w > ω) for various scaled total CD8 density xT. (C) The probability ℙ(w > ω) as a function of CD8 density xT, at a set value of functional sensitivity ω = 0.12. The operating range of the probability ℙ is shown as a function of xT with dashed lines at ℙ(w > 0.12) = 10−8 and ℙ(w > 0.12) = 10−5. Parameter values: δ = 300, ν = 0.5, n = 100, γkin = 0.5, γoff = 0.5, γR = 0.3, κ = 5, mT = 10, rT = 10. The log-normal distribution has mean 2 and SD 0.2.