Phase contrast photomicrographs of live BMMO grown on uniform pp-FC surfacespreconditioned with a single component BSA (3 mg/ml) solution, 100% FBS or 10% FBS. Cells were seeded at densities of 1500 cells/mm 2 Times indicated and scale bars are relevant for each row of images. Circles indicate “astral” morphology (A, E), arrows indicate filopodia (D, F, M, O) and bold arrows indicate membrane ruffling (D, F). Multiple cytoskeletal features (i.e., filopodia, membrane ruffling) are common features on many cells (e.g., D and F). Images are representative of multiple fields (≥ 3) and multiple replicates (≥ 2) for each test condition.