Table 3.

Modification of the change in birth weight (g) associated with bulky DNA adduct levels by maternal intake of fruits and vegetables during pregnancy.

Models	Low maternal intakea			High maternal intake			p-Valuec
	n	βb (95% CI)	p-Value	n	β (95% CI)	p-Value
Fruits and vegetables
Adducts (increase of 10 adducts/108 nt)	197	–22 (–80, 36)	0.45	212	–22 (–86, 42)	0.51	0.77
Low (< 5.9/108 nt)d	71	Reference		82	Reference
Middle (5.9–12.4/108 nt)	71	–78 (–217, 61)	0.27	69	–37 (–173, 100)	0.60	0.75
High (> 12.4/108 nt)	55	–248 (–405, –92)	0.002	61	–58 (–206, 90)	0.44	0.077
Fruit high in vitamin C
Adducts (increase of 10 adducts/108 nt)	201	–39 (–94, 15)	0.15	208	3 (–64, 70)	0.93	0.63
Low (< 5.9/108 nt)e	66	Reference		87	Reference
Middle (5.9–12.4/108 nt)	73	–120 (–259, 19)	0.09	67	–0 (–129, 128)	1.00	0.54
High (> 12.4/108 nt)	62	–266 (–421, –112)	0.001	54	–39 (–186, 107)	0.60	0.26
aLow corresponds to < 579 g/day, which is the overall median intake; high corresponds to ≥ 579 g/day in terms of fruits and vegetables. For fruit high in vitamin C, low corresponds to < 121 g/day and high corresponds to ≥ 121 g/day. bEffect estimates on birth weight (g) in linear regression models further adjusted; see Table 2. cp-Value for the interaction term between maternal intake (low, high) and bulky DNA adduct level in cord blood. dThe mean birth weight of the reference group was 3,613 g for low intake and 3,513 g for high intake. eThe mean birth weight of the reference group was 3,593 g for low intake and 3,534 g for high intake.