. Author manuscript; available in PMC: 2014 Oct 1.

Published in final edited form as: J Am Geriatr Soc. 2013 Sep 19;61(10):1743–1749. doi: 10.1111/jgs.12446

Table 3.

Association of Inflammation Score with Incident Inability to Complete the 400 m Walk at Follow-Up


	Models I^a		Models II^b		Models III^c		Models IV^d
	OR	(95% CI)	OR	(95% CI)	OR	(95% CI)	OR	(95% CI)
Inflammation score^‡
0	Reference		Reference		Reference		Reference
1 or 2	1.8	(1.2–2.8)	1.7	(1.9–2.8)	1.3	(0.8–2.3)	1.2	(0.7–2.1)
3 or 4	4.2	(2.2–7.9)	3.2	(1.6–6.4)	2.5	(1.2–5.0)	2.2	(1.0–5.0)
p for trend	p < 0.01		p < 0.01		p = 0.02		p = 0.09

^‡

Elevated = In the highest quartile for each cytokine:

Q1 = Quartile 1, Q2 = Quartile 2, Q3 = Quartile 3, Q4 = Quartile 4

OR = Odds Ratio; CI = Confidence Interval

Models I = Unadjusted bivariate models

Models II = Age and sex adjusted models

Models III = Adjusted for Model II covariates as well as body mass index, education, total number of medical conditions (includes arthritis, cancer, coronary heart disease, chronic obstructive pulmonary disease, diabetes, hip fracture, peripheral arterial disease, stroke)

Models IV = Adjusted for Model III and the following physiologic measures: MMSE, nerve conduction velocity, leg muscle power, serum hemoglobin, ankle-brachial index

Models I–III are based on an analysis sample of 1006 observations representing 621 respondents

Models IV are based on an analysis sample of 941 observations representing 621 respondents

p< 0.05 (bolded)