Figure 7.
Comparison of lyngbyoic acid (4) induced changes in gene expression (a) with previous studies of quorum-sensing controlled genes, Wagner et al.13 (b) and Schuster et al.12 (c and d). a) Cultures of PAO1 were treated with 1 mM 4 for 6 h at 37 °C with shaking. b) PAO-JP2 treated with exogenous 3-oxo-C12-HSL and C4-HSL. c) PAO-MW1 treated with 3-oxo-C12-HSL. d) PAO-MW1 treated with 3-oxo-C12-HSL and C4-HSL.