Table 1.
Reduction of SUMOylation enhances tbx-2(bx59) embryonic lethality and pharyngeal defects
| Genotypea | % embryonic arrest (n) | Pharyngeal phenotypes in hatched L1s (percentage of total hatched animals) | |||
|---|---|---|---|---|---|
| Severe Tbx-2 pharynx | Mild Tbx-2 pharynx | Wild-type pharynx | n | ||
| tbx-2(bx59) | 7 (120) | 19 | 56 | 25 | 54 |
| ubc-9(RNAi) | 19 (186) | 7 | 6 | 87 | 69 |
| tbx-2(bx59); ubc-9(RNAi) | 78 (200) | 70 | 30 | 0 | 47 |
| smo-1(RNAi) | 65 (347) | 22 | 39 | 39 | 49 |
| tbx-2(bx59); smo-1(RNAi) | 75 (359) | 69 | 26 | 5 | 64 |
aL4 animals raised at 16 °C were shifted to 25 °C, and defects were scored in the F1 progeny