Table 5.

Multivariable Associations With HRT Variables Representative of Each Principle Component

	Linear Cup-to-Disc Ratio			Mean RNFL Thickness, mm			Rim Area, mm2
	β	95% CI	P Value	β	95% CI	P Value	β	95% CI	P Value
Age, per decade	0.010	(0.004, 0.015)	0.001	−0.015	(−0.017, −0.012)	<0.001	−0.022	(−0.031, −0.013)	<0.001
Sex
Male	Ref			Ref			Ref
Female	0.004	(−0.008, 0.015)	0.52	0.006	(0.002, 0.011)	0.003	0.000	(−0.019, 0.018)	0.97
Height, per 10 cm	0.009	(0.002, 0.015)	0.008	0.003	(0.000, 0.005)	0.036	−0.010	(−0.020, 0.000)	0.06
BMI, per 5 kg/m2	−0.008	(−0.013, −0.004)	<0.001	0.001	(−0.001, 0.002)	0.37	0.013	(0.006, 0.020)	<0.001
SBP, per 10 mm Hg	−0.001	(−0.003, 0.001)	0.44	0.000	(−0.001, 0.001)	0.58	0.003	(−0.001, 0.007)	0.11
Education level
Degree	Ref			Ref			Ref
A level	0.010	(−0.001, 0.021)	0.06	−0.008	(−0.012, −0.004)	<0.001	−0.016	(−0.034, 0.001)	0.07
O Level	−0.003	(−0.017, 0.012)	0.71	−0.001	(−0.007, 0.004)	0.60	0.004	(−0.019, 0.027)	0.72
Less than O level	0.009	(−0.003, 0.021)	0.15	−0.009	(−0.014, −0.005)	<0.001	−0.014	(−0.034, 0.005)	0.15
Axial length, mm	0.002	(−0.001, 0.006)	0.18	−0.006	(−0.008, −0.005)	<0.001	−0.005	(−0.010, 0.001)	0.08
IOP, mm Hg	0.003	(0.002, 0.004)	<0.001	0.000	(−0.001, 0.000)	0.15	−0.005	(−0.006, −0.003)	<0.001
Lens status
Phakic	Ref			Ref			Ref
Pseudophakic	0.01s7	(0.003, 0.030)	0.016	−0.011	(−0.017, −0.006)	<0.001	−0.030	(−0.052, −0.008)	0.007

Results are from three multivariable linear regression models with the HRT variable as dependent variable, and all explanatory variables presented included together in each model. P values <0.01 are in bold.