Table 1.
Baseline Characteristics by Thyroid Function Group
| Baseline Thyroid Group |
Overall Thyroid Group |
|||||
|---|---|---|---|---|---|---|
| Baseline Characteristic |
Hyperthyroid at Baseline n = 20 (0.9%) |
Euthyroid at Baseline n = 1,930 (86.7%) |
Hypothyroid at Baseline n = 275 (12.4%) |
Hyperthyroid (Baseline + New Onset) n = 109 (4.9%) |
Euthyroid (at All Times) n = 1,500 (67.4%) |
Hypothyroid (Baseline + New Onset) n = 616 (27.7%) |
| Age (yrs) | 56.8 ± 14.7 | 59.2 ± 11.8 | 61.7 ± 12.0* | 54.5 ± 12.0† | 59.1 ± 11.7 | 61.5 ± 11.8† |
| Age >60 yrs | 40% (8) | 49% (947) | 60% (166)* | 32% (35)† | 48% (723) | 59% (363)† |
| Women | 35% (7) | 22% (417) | 41% (113)* | 22% (24) | 20% (296) | 35% (217)† |
| Nonwhite race | 25% (5) | 24% (454) | 18% (50)* | 26% (28) | 25% (377) | 17% (104)† |
| NYHA class III | 20% (4) | 29% (551) | 32% (88) | 27% (29) | 29% (428) | 30% (186) |
| Ischemic HF etiology |
40% (8) | 52% (996) | 51% (140) | 42% (46) | 52% (776) | 52% (322) |
| Ejection fraction (%) | 23.1 ± 6.4 | 23.9 ± 6.8 | 24.7 ± 6.9 | 24.2 ± 6.2 | 23.9 ± 6.9 | 24.2 ± 6.8 |
| 6-min walk distance (ft) |
1,080.4 ± 396.6 | 1,122.2 ± 398.5 | 1,091.0 ± 409.3 | 1,140.2 ± 395.1 | 1,126.6 ± 405.5 | 1,093.3 ± 385.8† |
Values are mean ± SD or % (n). Comparisons are with the euthyroid group within each classification, using Wilcoxon rank sum tests for continuous variables and likelihood ratio chi-square tests for categorical variables.
*
p < 0.05 for baseline group comparisons.
†p < 0.05 for overall group comparisons.
HF = heart failure; NYHA = New York Heart Association.