Brief (3 days) and prolonged (7 days) monocular deprivation of the dominant, contralateral eye, induced a significant decrease in the VEP contralateral bias in juvenile (P25) wild type, but not NARP −/− mice. Diazepam (DZ, for 5 days initiated at P25) enabled ocular dominance plasticity in NARP −/− mice. One way ANOVA (F6,29=51.187, p<0.001); *p<0.05 Bonferroni's post hoc versus WT no MD control. Normal VEP contralateral bias is depicted by grey horizontal bar. Inset: representative VEP waveforms. C=contralateral eye, I=ipsilateral eye. Scale bars: horizontal 50 ms, vertical 50 µV.