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. Author manuscript; available in PMC: 2014 Jul 24.
Published in final edited form as: Neuron. 2013 Jul 24;79(2):335–346. doi: 10.1016/j.neuron.2013.05.016

Fig 7. Absence of ocular dominance plasticity in adult NARP −/− mice.

Fig 7

Prolonged monocular deprivation (7 days) of the dominant, contralateral eye, initiated in adulthood (P90) and chronic monocular deprivation (from P21 – P100) induced a significant decrease in the VEP contralateral bias in adult wild type, but not NARP −/− mice. Diazepam (DZ, during the last 5 days of chronic MD) enabled ocular dominance plasticity in chronically- deprived NARP −/− mice, but does not change the ocular dominance shift in wild type mice. One way ANOVA (F7,32=18.706, p<0.001); *p<0.05 Bonferroni's post hoc versus WT no MD. Normal VEP contralateral bias is depicted by grey horizontal bar. Inset: representative VEP waveforms. C=contralateral eye, I=ipsilateral eye. Scale bars: 50 ms, 50 µV.