Table 1.

Quantitative summary of MT-stabilizing trends for MAP4 in the presence and absence of Taxol.

Interface	Total ΔHDX (α)		P	Total ΔHDX (β)		P
	MAP4	MAP4+Taxol		MAP4	MAP4+Taxol
Interdimer	−136 ± 38	−118 ± 40	0.6	−270 ± 18	−246 ± 18	0.1
Intradimer	−108 ± 43	−292 ± 54	0.003	−184 ± 24	−441 ± 36	0.000
Lateral	−142 ± 15	−17 ±21	0.001	−81 ± 41	−298 ± 43	0.001

^*Peptide α154-166 was not included in the total ΔHDX calculation at the interdimer interface for reasons referred to in the “Results” section.