Illustration of the notion of effective foci and effective channels.
1 – section of squamous layer opposite to an initial lymph capillary (ILC); (2) –____ channels with ∼100 nm diameter between the ILC and the squamous layer;
• • • •foci
Only channels 1 and 5 have contact with foci and contribute to nanoparticles transport. Only foci 1 and 5 are effective. Other foci do not contribute to nanoparticles transport. Channels perpendicular to the drawn channels are normally not shown. Channels are normally not straight.