Table 1.
Relationship Between Clinical Characteristics and Obesity at Baseline
| |
Obese (≥95th percentile for BMI) |
|
||
|---|---|---|---|---|
| Variable | No | Yes | % | pa |
| Therapy | ||||
| Olanzapine (n=72) | 62 | 10 | 13.9 | |
| Placebo (n=35) | 28 | 7 | 20 | 0.41 |
| Race | ||||
| White (n=77) | 67 | 10 | 13 | |
| Non-white (n=30) | 23 | 7 | 23.3 | 0.24 |
| Gender | ||||
| Female (n=32) | 23 | 9 | 28.1 | |
| Male (n=75) | 67 | 8 | 10.7 | 0.04 |
| Psychiatric hospitalization (previous year) | ||||
| No (n=47) | 43 | 4 | 8.5 | |
| Yes (n=60) | 47 | 13 | 21.7 | 0.11 |
| Psychotic features (current) | ||||
| No (n=80) | 69 | 11 | 13.8 | |
| Yes (n=27) | 21 | 6 | 22.2 | 0.36 |
| Psychotic features (lifetime) | ||||
| No (n=79) | 68 | 11 | 13.9 | |
| Yes (n=28) | 22 | 6 | 21.4 | 0.38 |
| Mean (SD) | Mean (SD) | t | p | Effect sizeb | |
|---|---|---|---|---|---|
| n=70 | n=15 | ||||
| Previous episodes | 2.41 (3.81) | 2.53 (2.13) | −0.17 | 0.87 | 0.03 |
| n=90 | n=17 | ||||
| Onset age | 12.73 (3.15) | 13.29 (2.69) | −0.69 | 0.49 | 0.18 |
| CGI Severity | 4.92 (0.74) | 4.59 (0.62) | 1.75 | 0.08 | 0.46 |
| OAS total score | 1.91 (2.52) | 2.94 (3.78) | −1.08 | 0.29 | 0.38 |
| PANSS total score | 96.38 (14.11) | 89.33 (12.46) | 1.77 | 0.08 | 1.31 |
| Positive total | 22.73 (5.04) | 22.65 (4.08) | 0.07 | 0.95 | 0.02 |
| Negative total | 25.64 (5.37) | 20.59 (6.25) | 3.47 | <.01 | 0.91 |
| BPRS-C Total Score | 50.63 (9.06) | 47.94 (11.62) | 1.07 | 0.29 | 0.29 |
a
Fisher's exact test.
b
Cohen's d effect size.
BMI, body mass index; BPRS-C, Brief Psychiatric Rating Scale for Children; CGI, Clinical Global Impressions Scale; OAS, Overt Aggression Scale; PANSS, Positive and Negative Syndrome Scale.