Table 2.
Synthesis of PEG-polypeptide dual brush block copolymers
| entry | polymer | micro-initiator | monomer [M]/[I] | conv (%)a | dn/dc (mL/g)b | Mn (Mn*) (× 10−4)c | MWDc | |
|---|---|---|---|---|---|---|---|---|
| 1 | P1-g-Glu20 | P1 | Glu-NCA | 20 | >95 | 0.080 | 14.3 (15.7) | 1.05 |
| 2 | P1-g-Glu40 | P1 | Glu-NCA | 40 | >95 | 0.086 | 20.6 (24.4) | 1.04 |
| 3 | P2-g-Glu20 | P2 | Glu-NCA | 20 | >95 | 0.083 | 25.0 (28.5) | 1.08 |
| 4 | P2-g-Glu40 | P2 | Glu-NCA | 40 | >95 | 0.088 | 38.7 (46.0) | 1.09 |
| 5 | P3-g-Glu20 | P3 | Glu-NCA | 20 | >95 | 0.081 | 26.4 (31.1) | 1.06 |
| 6 | P1-g-Lys20 | P1 | Lys-NCA | 20 | >95 | 0.082 | 13.3 (16.9) | 1.09 |
a
The conversion of monomer was determined by FT-IR
b
The dn/dc values were calculated offline by using the internal calibration system processed by the ASTRA V software
c
The MW obtained by GPC (the expected MW).