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. 2013 Sep 29;2013:379870. doi: 10.1155/2013/379870

Table 3.

Comparative differences in frequency of grade 3 neurological adverse effects with grade 1 and grade 2 adverse effects.

Paired samples test
Toxicity Mean Std. deviation Mean difference t df P value
Taste disturbance grade 1, 2 3.816 3.525 3.789 6.608 37.000 0.000
Taste disturbance grade 3 0.026 0.162
Headache grade 1, 2 2.053 2.588 2.053 4.888 37.000 0.000
Headache grade 3 0.000 0.000
Paresthesia grade 1, 2 5.079 3.529 5.079 8.872 37.000 0.000
Paresthesia grade 3 0.000 0.000
Dizziness grade 1, 2 1.474 2.345 1.474 3.874 37.000 0.000
Dizziness grade 3 0.000 0.000
Insomnia grade 1, 2 1.474 2.357 1.474 3.855 37.000 0.000
Insomnia grade 3 0.000 0.000
Peripheral neuropathy grade 1, 2 4.947 3.385 4.395 7.045 37.000 0.000
Peripheral neuropathy grade 3 0.553 1.589
Hypoaesthesia grade 1, 2 4.526 4.105 4.526 6.797 37.000 0.000
Hypoaesthesia grade 3 0.000 0.000

P value < 0.05 (significant), P value < 0.01 (highly significant), and P value < 0.001 (very highly significant).