Table 5.
Comparative differences in incidence rate of neurological adverse effects between each treatment arm of FOLFOX.
| ANOVA | ||
|---|---|---|
| Toxicity | F | P value |
| Neurological | ||
| Taste disturbance | 4.370 | 0.010 |
| Headache | 1.169 | 0.336 |
| Paresthesia | 3.475 | 0.026 |
| Dizziness | 3.458 | 0.027 |
| Insomnia | 0.955 | 0.425 |
| Peripheral neuropathy | 5.077 | 0.005 |
| Hypoaesthesia | 3.598 | 0.023 |
P value < 0.05 (significant), P value < 0.01 (highly significant), and P value < 0.001 (very highly significant).