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18F-FDHT PET images at baseline (A) and after 4 weeks of treatment with enzalutamide (B). The sagittal and coronal images were taken 1 h after administration of 18F-FDHT. After four weeks, they show a reduction in 18F-FDHT accumulation in tumor within the vertebrae, compared with the cardiac and aortic blood pool. Reproduced with permission from Scher et al [61].
