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. 2013 Sep 10;1(4):e00081. doi: 10.1002/phy2.81

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© 2013 The Author. Physiological Reports published by John Wiley & Sons Ltd on behalf of the American Physiological Society and The Physiological Society

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Cumulative concentration–response curves (left) and logEC50 (right) to endothelial-dependent vasorelaxation to acetylcholine (ACh) (A) in third-order mesenteric arteries from lean MC4R+/+ and obese MC4R+/− pregnant rats at GD 19. Raw tracings to ACh in MC4R+/+ (B) and MC4R+/− (C). Cumulative concentration–response curves (left) and logEC50 (right) to the nitric oxide donor sodium nitroprusside (SNP) (D). *P < 0.05 versus MC4R+/+.