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Bromophycolide A (1) decreases parasitemia in vivo. BrA (1) was administered to Swiss webster female mice on day 2 after confirmation of infection with Plasmodium yoelii. Experiment was terminated on day 5 and daily parasite load determined by FACS analysis by staining the parasites with Hoechst 33342 (n = 3; ± standard deviation [SD]).
