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. 2013 Sep 2;4(10):989–993. doi: 10.1021/ml4002858

Table 1. Pharmacokinetic Parameters Following Either Intravenous Bolus (IV) or Intraperitoneal (IP) Injection of BrA (1) in Mice (n = 3; mean ± SD).

parameter units IV IP
dose mg/kg 23 23
Kel h–1 0.93 ± 0.13  
Kab h–1   0.24 ± 0.03
t1/2 h 0.75 ± 0.11  
Cmax μg/mL   5.8 ± 3.9
Tmax h   1.5
AUC μg·h/mL 26 ± 5 20
Cp0 μg/mL 24 ± 6  
Vd L/kg 0.95 ± 0.27  
CL mL/min/kg 16 ± 3