Table 1. List of bleomycin-induced genes modulated by col(V) treatment.

		Gene		Bonferroni-adjusted P value
Functional Class	Unigene	Symbol	Gene Description	Upregulation	Downregulation
				PBS vs BLEO	BLEO vs BLEO+COL(V)
Integrins
	Mm.5007	Itga2	Integrin alpha 2	0.001	0.001
	Mm.57035	Itga3	Integrin alpha 3	0.05	0.001
	Mm.263396	Itb1	Integrin beta 1 (fibronectin receptor beta)	0.001	0.001
	Mm.98193	Itb6	Integrin beta 6	0.01	0.01
Cytokines/Growth Factors
	Mm.248380	Tgfb1	Transforming growth factor, beta 1	0.05	0.01
	Mm.222830	Il1b	Interleukin 1 beta	0.001	0.001
	Mm.144089	Pdgfb	Platelet derived growth factor, B polypeptide	0.05	0.05
Fibrosis, matrix and matrix-binding molecules
	Mm.213025	Acta2	Actin, alpha 2, smooth muscle, aorta	0.05	0.01
	Mm.277792	Col1a2	Collagen, type I, alpha 2	0.05	0.05
	Mm.249555	Col3a1	Collagen, type III, alpha 1	0.05	0.05
	Mm.172	Lox	Lysyl oxidase	0.01	0.01
	Mm.29564	Mmp2	Matrix metallopeptidase 2	0.05*	0.05*
	Mm.439656	Cebpb	CCAAT/enhancer binding protein (C/EBP), beta, latency associated peptide (LAP)	0.05*	0.05*
Members of the TGF-beta superfamily
	Mm.197552	Tgfbr1	Transforming growth factor, beta receptor I, ALK5	0.05	0.01
	Mm.172346	Tgfbr2	Transforming growth factor, beta receptor II	0.001	0.001
	Mm.269747	Ltbp1	Latent transforming growth factor beta binding protein 1	0.01	0.01
	Mm.391091	Smad2	MAD homolog 2 (Drosophila)	0.01	0.05
	Mm.7320	Smad3	MAD homolog 3 (Drosophila)	0.05	0.05
	Mm.250422	Serpine1	Serine (or cysteine) peptidase inhibitor, clade E, member 1, PAI-1	0.05	0.05
Transcription factors
	Mm.2093	Snai1	Snail homolog 1 (Drosophila)	0.05*	0.01*
	Mm.256765	Nfkb	Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105	0.05	0.05
	Mm.4618	Sp1	Trans-acting transcription factor 1	0.05	0.05
	Mm.121721	Stat6	Signal transducer and activator of transcription 6	0.01	0.01

^*indicates Newman-Keul's-adjusted P value.