Figure 5. Co-expression of inhibitory receptors on CD8⁺ and CD4⁺ T cells in chronically HIV-infected BLT mice.

A) Representative flow cytometry data of peripheral blood from an HIV-infected BLT mouse at 13 weeks post infection. Co-expression of CD244, CD160, and LAG-3 with PD-1 was determined on human CD8⁺ and CD4⁺ cells. B) Percentages of PD-1 expressing CD8⁺ and CD4⁺ T cells co-expressing CD244, CD160, and LAG-3 at 13 weeks and 26 weeks post infection. Horizontal lines within data points depict mean values. *P = 0.036, Mann-Whitney test.