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. 2013 Oct 16;8:3977–3990. doi: 10.2147/IJN.S52058

Figure 1.

Figure 1

The morphological and physicochemical properties of the PEG-USPIO were investigated.

Notes: Images (A) and (B) revealed the size of the iron core (bar =100 nm and =20 nm, respectively). (C) TEM picture of the PEG-USPIO (bar =20 nm). (D) The magnetic property of the PEG-USPIO was assessed by the MPMS. (E) DLS assay demonstrates that the hydrodynamic size of the nanoparticle was approximately 28 nm. (F) The C13 NMR spectrum of PEG-OH (below) and PEG-COOH (above). The presence of a carboxyl group peak at 163.8 ppm (red frame) indicates the carboxylation of the terminal hydroxyl.

Abbreviations: DLS, dynamic light scattering; MPMS, magnetic property measurement system; NMR, nuclear magnetic resonance; PEG-USPIO, polyethylene glycol-coated ultrasmall superparamagnetic iron oxide; TEM, transmission electron microscope.