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. 2013 Oct 16;8:3977–3990. doi: 10.2147/IJN.S52058

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© 2013 Yang et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License

The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

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(A) T2-weighted MRI of PEG-USPIO or Bcl-2-USPIO diluted with DI water, in tubes with increasing iron concentrations. (B) 1/T2 versus iron concentration of PEG-USPIO or Bcl-2-USPIO and analyzed by linear equation.^a

Notes: ^a(PEG-USPIO: y =2.3236x + 2.3863, R2 =0.9879; Bcl-2-USPIO: y =1.0858x + 2.5726, R2 =0.9796).

Abbreviations: Bcl, B-cell lymphoma; Bcl-2-USPIO, Bcl-2-functionalized ultrasmall superparamagnetic iron oxide; DI, deionized; Fe, iron; MRI, magnetic resonance imaging; PEG-USPIO, polyethylene glycol-coated ultrasmall superparamagnetic iron oxide.