Table 1. Genotype frequency of pups derived from heterozygous intercrosses.
| Age examined | Total number examined | Etv5WT/WT | Etv5WT/sco | Etv5sco/sco | |||
| % Expected | % Observed | % Expected | % Observed | % Expected | % Observed | ||
| E10.5–E13.5 | 95 | 25 | 24.2 (23/95) | 50 | 52.6 (50/95) | 25 | 23.2 (22/95) |
| E14.5–E18.5 | 85 | 25 | 27.1 (23/85) | 50 | 57.6 (49/85) | 25 | 15.3* (13/85) |
| 1 week | 112 | 25 | 30.3 (34/112) | 50 | 59.0 (66/112) | 25 | 10.7** (12/112) |
| 3 weeks | 312 | 25 | 33.0 (103/312) | 50 | 58.7 (183/312) | 25 | 8.3%** (26/312) |
*
p<0.05;
**
p<0.001 (unpaired t-test, two-tailed). A shift in the ratio of Etv5WT/WT and Etv5WT/sco mice obtained at E14.5–E18.5, 1 week and 3 weeks was due to the lost of Etv5sco/sco mice.