Figure 5. Bladder mBD-14 protein expression is induced by UPEC infection.
Naïve and infected bladders harvested at indicated hpi were subject to mBD-14 IHC and counterstained with hematoxylin. Whereas mBD-14 is undetectable in uninfected bladder, it is expressed throughout the urothelium as early as 2 hpi, with increased expression by 6 hpi (black arrows) that persists at subsequent timepoints. 100x magnification.
