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CCL5 is mainly expressed by inflammatory cells in TME and some cancer cells in patient samples as shown by immunostaining with Pab CCL5, but only sparse CAFs are positive for CCL5 (A, B). CaDEC12 cells, the primary cultures of CAFs obtained from tongue cancer patients, express relative amount of CCL5 compared to NOFs, normal oral fibroblasts (C). Scale bar 100 µm.
