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Exosite of MMP13 interacts with TIMP-2. B-type peptides interact with the same area as the TIMP-2 AB loop in MMP-13 (2E2D). B-type peptide contacts (green) and contacts shared with TIMP-2 (red). (Phe175 of MMP-13 is in a different conformation in MMP-13-TIMP-2 and is not highlighted.) TIMP-2 structure (blue).
