Table 3.
Grade 2 and 3 toxicities associated with the CapOx regimen (total n. patients=24).
| Grade 2 (N) | % | Grade 3 (N) | % | Total n. | % of total | |
|---|---|---|---|---|---|---|
| Overall toxicity | ||||||
| Grade 2 | 15 | 63 | ||||
| Grade 3 | 6 | 25 | ||||
| CapOx dose reduction | 8 | 33 | ||||
| Hospitalizations | ||||||
| Disease-related | 4 | 17 | ||||
| Treatment-related | 0 | 0 | ||||
| Infection (not due to neutropenia) | 3 | 13 | ||||
| Main reported toxicities | ||||||
| Neuropathy | 7 | 29 | 2 | 8 | 9 | 37 |
| Hand-foot syndrome | 3 | 13 | 1 | 4 | 4 | 17 |
| Diarrhea | 1 | 4 | 2 | 8 | 3 | 12 |
| Hematologic toxicity (neutropenia) | 1 | 4 | 0 | 0 | 1 | 4 |
| Nausea | 2 | 8 | 0 | 0 | 2 | 8 |
| Asthenia | 1 | 4 | 0 | 0 | 1 | 4 |
| Oxaliplatin hypersensibility reaction | 0 | 0 | 1 | 4 | 1 | 4 |