Figure 1. The sequence of human FKBP38.

The domain organization of FKBP38 is shown, along with a graphical representation of the constructs used in the current study. Above, the N-terminal 32 residues of FKBP38 and sequence alignment of the C-terminus of all TPR-containing human FKBPs, within which FKBP37 and FKBP38 are predicted to encode calmodulin binding domains. SS is the consensus secondary-structure prediction for all listed proteins³³; numbering is according to FKBP38. FKBP, FKBP binding domain; TPR, tetratricopeptide repeats; TM, transmembrane domain; NTD, N-terminal domain.