Fig. 3.

Skeletal muscle substrate storage and capacity for oxidation before (white bars) and after (black bars) a 16 week lifestyle intervention of DIWL (n=8) or EX (n=8). All measures were performed on biopsy samples of the vastus lateralis. IMCL content, as determined by Oil Red O staining (a); SDH activity staining (b); and glycogen content (c) were determined using histochemical analyses as described in Methods. Data are mean ± SEM. Group and intervention effects were explored using a two-way (group×time) repeated-measures ANOVA. *p<0.05 within-group intervention effect; ^†p<0.05 between-groups difference