Table 3.
Biochemical parameters before and after parathyroid adenomectomy (PTX).
| Baseline | After PTX | ||||
|---|---|---|---|---|---|
| Median | IQR | Median | IQR | P (W) | |
| S-25-OH-D (75–250 nmol/l) | 40 | 31–49 | 42 | 33–54 | 0.004 |
| P-PTH (10–65 ng/l) | 116 | 89–145 | 65 | 53–68 | <0.001 |
| S-Ca2+ (1.15–1.33 mmol/l) | 1.43 | 1.39–1.43 | 1.25 | 1.22–1.27 | <0.001 |
| P-phosphate (0.75–1.4 mmol/l) | 0.83 | 0.74–0.92 | 1.0 | 0.92–1.1 | <0.001 |
| P-creatinine (♀<90, ♂<100 μmol/l) | 65 | 56–76 | 67 | 58–75 | 0.400 |
| GFR creatinine (ml/min) | 97 | 79–117 | 95 | 79–115 | 0.900 |
| P-glucose (4.0–6.0 mmol/l)a | 5.2 | 4.9–5.6 | 5.2 | 4.8–5.6 | 0.022 |
| S-insulin (18–173 pmol/l)a | 66 | 43–97 | 58 | 37–95 | <0.001 |
| HOMA-IRa | 2.2 | 1.4–3.3 | 1.8 | 1.2–3.2 | <0.001 |
| S-IGF1 (110–270 μg/l) | 144 | 117–179 | 138 | 115–172 | <0.001 |
| S-IGFBP1 | 30 | 21–49 | 37 | 21–54 | 0.046 |
| S-cholesterol (3.3–7.8 mmol/l) | 5.6 | 4.8–6.1 | 5.5 | 4.9–6.3 | 0.134 |
| P-HDL (♀01.0–2.7, ♂0.8–2.1 mmol/l) | 1.4 | 1.2–1.8 | 1.4 | 1.2–1.8 | 0.825 |
| P-LDL (1.4–5.3 mmol/l) | 3.5 | 2.8–4.1 | 3.5 | 2.8–4.1 | 0.161 |
| S-triglycerides (0.45–2.6 mmol/l) | 0.98 | 0.75–1.40 | 0.96 | 0.70–1.52 | 0.256 |
W, Wilcoxon signed-rank sum test for paired data; 25-OH-D, 25-hydroxyvitamin D; PTH, parathyroid hormone; Ca2+, ionized calcium; GFR, glomerular filtration rate; HOMA-IR, homeostatic model assessment insulin resistance; IGF1, insulin-like growth factor 1; IGFBP1, IGF-binding protein 1.
a
Patients with insulin treatment were excluded from the analysis.