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Inconsistent synteny of β2M among vertebrate species. Genomic synteny of β2M is not consistent in bony fish and Xenopus, suggesting that multiple translocations of β2M occurred over evolutionary time. An asterisk (*) indicates the location of the β2M gene, and brackets indicate the genomic regions corresponding with the particular human chromosome. The detailed gene assignments can be obtained in Supplemental Table II. IgH and TCRα loci are marked in opossum chromosome 1.
