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Glomerular amyloid spicules. Glomerular amyloid spicules (arrows) result from parallel alignment of amyloid fibrils in the subepithelial zone perpendicular to the glomerular basement membrane. They were more common in AL/AH/AHL than other types of amyloidosis (Jones methenamine silver). The small image shows amyloid spicules by electron microscopy. AL/AH/AHL, light chain/heavy chain/heavy and light chain amyloidosis. Original magnification, ×400 in image; ×23,000 in inset.
