Table 4.
Case No. | LMD/MS | Positive Immunoreactants on Immunofluorescence |
---|---|---|
1 | AL-κ | κ (1+), λ (+/−), IgG (+/−), IgM (+/−), C3 (+/−) |
2 | AL-κ | κ (3+), λ (2+), IgG (2–3+), C3 (2–3+) |
3 | AL-κ | κ (1+), λ (1+), IgA (1+), IgG (+/−), IgM (2+) |
4 | AL-κ | κ (3+), IgA (3+) |
5 | AL-λ | λ (2+), κ (1–2+), IgM (3+) |
6 | AL-λ | λ (1–2+), κ (+/−), IgG (1–2+) |
7 | AL-λ | λ (1+), κ (1+), C3 (3+) |
8 | AL-λ | λ (1+), κ (+/−), IgM (1+), IgG (+/−), IgA (+/−), C3 (+/−), C1q (+/−) |
9 | AL-λ | λ (2+), IgG (2+), IgM (+/−), C3 (+/−) |
10 | AL-λ | λ (3+), IgG (2+) |
11 | AL-λ | λ (1+), κ (1+), IgG (1+), IgA (1+), IgM (1+) |
12 | AL-λ | λ (2+), IgG (1–2+), IgM (+/−) |
13 | AL-λ | λ (1+), κ (1+) |
Numbers in parentheses indicate the intensity of staining on a scale of 0–3+; negative immunoreactants are not listed. AL, light chain amyloidosis; LMD/MS, laser microdissection/mass spectrometry.