Table 1. Effect of topical application of B. lanzan on excision wounds in rat.
Group | Mean wound area (mm2) ± SEM (% contraction) |
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0 day | 3rd day | 6th day | 9th day | 12th day | 15th day | |
Vehicle control | 318.00±8.65 | 270.00±8.33 (15) | 213.00±7.18 (33.01) | 139.00±6.01 (56.28) | 80.00±5.10 (74.84) | 46.00±2.80 (85.53) |
Soframycin (1%) | 303.00±8.39 | 238.00±8.58 (21.45) | 136.00±9.97 (55.11)** | 47.00±6.40 (84.48)** | 16.00±2.10 (94.71)** | 6.00±0.52 (98.01)* |
B. lanzan (5%) | 314.00±8.55 | 272.00±7.76 (13.37) | 206.00±6.12 (34.39) | 129.00±7.71 (58.91) | 72.00±5.79 (77.07) | 35.00±3.50 (88.85) |
B. lanzan (10%) | 307.00±10.14 | 268.00±8.09 (12.70) | 188.00±9.96 (38.76) | 82.00±7.51 (73.28)* | 38.00±6.78 (87.62)* | 14.00±2.68 (95.43)* |
Values are expressed as mean±SEM (% wound contraction), n=6, *P<0.05, **P<0.01 vs. control by one way-ANOVA followed by Dunnet's Test.