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. 2013 Oct 22;7:169. doi: 10.3389/fncir.2013.00169

FIGURE 3.

FIGURE 3

LP Ih activity-dependence curve in 5 μM DA. (A) Experimental protocol: TEVC was used to create a recurring voltage step that mimicked slow wave activity at t = -10 min, except the length of the depolarizing step varied across experiments to alter burst duration. Examples are shown for how the length of the step corresponded to no change, a reduction or an increase in burst duration. There was no change in cycle period. (B) Plot of fold-changes in LP Ih Gmax for the 10 min time point; -100 on the x-axis represents experiments in TTX without a recurring step; vertical dashed line marks 30% reduction in burst duration (i.e., average 5 μM DA-induced change) each diamond represents one experiment; data were fitted with a Boltzmann sigmoidal equation.