Table 2.
Operative and early postoperative variables
| Parameter | All patients (n = 142) | Control (n = 64) | Delirium (n = 78) | Univariate |
|---|---|---|---|---|
| Mean ± SD (%) | Mean ± SD (%) | Mean ± SD (%) | P-value | |
| At Operation | ||||
| Operation time (h) | 2.89 ± 0.84 | 2.70 ± 0.57 | 3.04 ± 0.99 | 0.020a |
| CPB time (h) | 1.49 ± 1.01 | 1.40 ± 1.29 | 1.56 ± 0.70 | 0.37 |
| Haemoglobin, lowest recorded (g/l) | 87.8 ± 10.7 | 86.9 ± 10.0 | 88.5 ± 11.3 | 0.37 |
| Aortic plaque (presence) | 22.4 | 16.4 | 27.4 | 0.13 |
| Lowest SAP (mmHg) | 76.5 ± 8.6 | 76.3 ± 8.0 | 76.7 ± 9.2 | 0.82 |
| Lowest DAP (mmHg) | 43.2 ± 6.5 | 43.3 ± 5.8 | 43.1 ± 7.1 | 0.86 |
| Lowest oxygen saturation (%) | 96.9 ± 2.1 | 97.2 ± 1.6 | 96.6 ± 2.4 | 0.079a |
| Arrhythmia, treatment required (yes) | 32.4 | 28.1 | 36.0 | 0.32 |
| Blood glucose >10 mM (yes) | 19.5 | 13.6 | 24.6 | 0.12 |
| Insulin infusion required (yes) | 16.7 | 9.5 | 22.7 | 0.045a |
| Tranexamic acid used (yes) | 57.9 | 54.7 | 60.5 | 0.49 |
| Adrenalin required (yes) | 10.0 | 12.5 | 7.9 | 0.37 |
| Milrinone required (yes) | 20.0 | 20.3 | 19.7 | 0.93 |
| Phenylephrine required (yes) | 22.9 | 23.4 | 22.4 | 0.88 |
| Norepinephrine required (yes) | 96.4 | 95.3 | 97.4 | 0.52 |
| Blood products required (yes) | 12.7 | 7.8 | 16.7 | 0.12 |
| Blood loss (l) | 0.46 ± 0.38 | 0.39 ± 0.30 | 0.51 ± 0.43 | 0.079a |
| Diuresis (l) | 0.79 ± 0.37 | 0.74 ± 0.40 | 0.82 ± 0.34 | 0.22 |
| Volume load, blood excluded (l) | 3.73 ± 1.05 | 3.44 ± 0.58 | 3.98 ± 1.26 | 0.003a |
| In the ICU | ||||
| ICU time (h) | 22.4 ± 19.5 | 18.2 ± 5.5 | 25.8 ± 25.4 | 0.013b |
| Ventilator time (h) | 7.42 ± 7.89 | 5.92 ± 2.01 | 8.65 ± 10.36 | 0.005a |
| Lowest SAP (mmHg) | 80.8 ± 12.6 | 80.5 ± 11.3 | 81.0 ± 13.6 | 0.80 |
| Lowest DAP (mmHg) | 42.8 ± 8.3 | 43.4 ± 8.5 | 42.3 ± 8.1 | 0.42 |
| Lowest oxygen saturation (%) | 94.7 ± 2.1 | 95.1 ± 2.1 | 94.3 ± 2.0 | 0.021a |
| Highest temperature recorded (°C) | 37.1 ± 0.5 | 37.0 ± 0.5 | 37.2 ± 0.5 | 0.068a |
| Pulse rate (beats/min) | 81.0 ± 13.4 | 80.9 ± 13.2 | 81.1 ± 13.6 | 0.95 |
| Pulse type (not SR) | 10.6 | 9.4 | 11.5 | 0.95 |
| Bleeding, recorded at 8 h (l) | 0.53 ± 0.32 | 0.51 ± 0.28 | 0.54 ± 0.36 | 0.60 |
| Haemoglobin, lowest recorded (g/l) | 95.0 ± 11.1 | 96.0 ± 11.4 | 94.2 ± 10.8 | 0.34 |
| Blood products required (yes) | 33.8 | 29.7 | 37.2 | 0.35 |
| Sodium concentration (mmol/l) | 138.1 ± 2.4 | 137.6 ± 2.4 | 138.5 ± 2.4 | 0.033a |
| Potassium concentration (mmol/l) | 4.91 ± 0.35 | 4.91 ± 0.36 | 4.92 ± 0.34 | 0.88 |
| Creatinine concentration (mg/l) | 83.0 ± 24.4 | 81.8 ± 25.9 | 84.1 ± 23.3 | 0.57 |
| Leucocyte count (109/l) | 10.9 ± 3.3 | 10.8 ± 3.5 | 11.0 ± 3.1 | 0.75 |
| Haemoglobin (g/l) | 104.0 ± 11.5 | 104.6 ± 13.2 | 103.6 ± 10.1 | 0.61 |
| Platelet count (109/l) | 162.4 ± 43.3 | 168.3 ± 41.6 | 157.6 ± 44.3 | 0.14 |
| Troponin-T (ng/l) | 0.37 ± 0.36 | 0.38 ± 0.40 | 0.37 ± 0.33 | 0.83 |
aDenotes variables tested in multivariable models, with a P-value of <0.10.
bDenotes variables (P < 0.10) avoided in the multivariable models because of covariability against other used parameters. Percent values or mean values ± SD.
CPB: cardiopulmonary bypass; SAP: systolic arterial blood pressure; DAP: diastolic arterial blood pressure; ICU: intensive care unit; SR: sinus rhythm. P-values refer to univariate logistic regression analyses.