Figure 4.

Plasma PIIINP is elevated in a second cohort of patients with tuberculosis (TB) of mixed human immunodeficiency virus (HIV) seroprevalence and correlates with tissue damage on chest radiographs. PIIINP concentrations were analyzed in a second cohort recruited in Durban, South Africa, of mixed HIV seroprevalence. (A) Plasma PIIINP was significantly increased in patients with tuberculosis. (B) Plasma PIIICP concentration showed a trend towards increase in tuberculosis that did not achieve statistical significance. (C) Plasma PIIINP concentration was elevated in patients with an abnormal CXR compared to those with a normal radiograph. (D) Patients with cavitary pulmonary tuberculosis assessed by chest radiography had higher plasma PIIINP concentrations than those without cavities.