Table 1.

Parameters describing isolated work-performing NTG and TG mouse hearts

Parameters	NTG, n = 6	β-TM TG, n = 5	γ-TM TG, n = 5	βγ-DTG, n = 5
Systolic pressure (mmHg)	124 ± 4.8	89.9 ± 2.3**	118.4 ± 5.7	120.3 ± 5.9
Diastolic pressure (mmHg)	−9.9 ± 3.0	−1.9 ± 1.8*	−5.62 ± 1.4	−6.6 ± 2.3
End diastolic pressure (mmHg)	3.4 ± 0.84	3.6 ± 0.2	3.8 ± 1.3	4.6 ± 1.9
Maximal rate of pressure development (+dP/dt) (mmHg/s)	3335 ± 142	2612 ± 150**	3792 ± 101*	3779 ± 53**
Maximal rate of pressure decline (−dP/dt) (mmHg/s)	3097 ± 242	2247 ± 84**	3707 ± 94*	3485 ± 161
Time to peak pressure (TPP) (ms/mmHg)	0.45 ± 0.019	0.58 ± 0.018**	0.37 ± 0.022*	0.43 ± 0.027
Half time to relaxation (RT½) (ms/mmHg)	0.6 ± 0.022	0.76 ± 0.025**	0.55 ± 0.024	0.58 ± 0.026
Heart rate (beats/min)	262 ± 21	290 ± 13	325 ± 16	304 ± 13

^*P < 0.05,

^**P < 0.01, NTG vs. TG