Table 2.

Parameters describing Ca²⁺-dependent activation of tension in skinned fiber bundles from NTG and TG hearts

Mouse model sarcomere length (μm)	pCa50	Δ pCa	nH	Tension (mN/mm2)	n
NTG 1.9	5.79 ± 0.004*	0.14 ± 0.02	3.31 ± 0.10	27.37 ± 4.51#	9
NTG 2.3	5.95 ± 0.01		2.94 ± 0.17	28.79 ± 3.66
γ-TM TG 1.9	5.72 ± 0.03*†	0.17 ± 0.01	2.53 ± 0.34	33.74 ± 4.06#	8
γ-TM TG 2.3	5.88 ± 0.01†		3.37 ± 0.14	34.93 ± 4.33
β-TM TG 1.9	5.82 ± 0.003*	0.18 ± 0.03	3.13 ± 0.06	27.35 ± 1.84#	11
β-TM TG 2.3	5.99 ± 0.01		3.62 ± 0.37	29.00 ± 2.66
βγ-TM 1.9	5.70 ± 0.01*†	0.12 ± 0.03	2.91 ± 0.37	20.71 ± 2.57**#	8
βγ-TM 2.3	5.85 ± 0.01†		3.31 ± 0.14	23.15 ± 2.56**

^*P < 0.05 between SL 1.9 and 2.3 μm in all groups

^†P < 0.05 for pCa₅₀ compared to NTG and β-TM TG at the both SL

^**P < 0.05 between βγ-TM maximum tension at SL 1.9 and 2.3 μm compared with the rest of the groups at the same SL

^#P < 0.05 tension for between SL 1.9 and 2.3 μm