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. Author manuscript; available in PMC: 2014 Jun 4.
Published in final edited form as: Structure. 2013 May 16;21(6):1042–1050. doi: 10.1016/j.str.2013.04.010

Fig. 4. Sequence Conservation of A3F loops with regions of HIV-1 Vif.

Fig. 4

(A): The 305-RLYYFWD-311 motif of the A3F-CTD β4-α4 loop is conserved across human

APOBEC3 protein domains and reappears in HIV-1 Vif.

(B): Sequence alignment of the 305-RLYYFWD-311 motif of the A3-CTD β4-α4 loop across a wide array of mammalian APOBEC3 proteins.

(C): The 223-EVVKHHSPVS-232 motif of the A3F-CTD β1-β2 loop is conserved in HIV-1 Vif.