(A): The 305-RLYYFWD-311 motif of the A3F-CTD β4-α4 loop is conserved across human
APOBEC3 protein domains and reappears in HIV-1 Vif.
(B): Sequence alignment of the 305-RLYYFWD-311 motif of the A3-CTD β4-α4 loop across a wide array of mammalian APOBEC3 proteins.
(C): The 223-EVVKHHSPVS-232 motif of the A3F-CTD β1-β2 loop is conserved in HIV-1 Vif.