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. Author manuscript; available in PMC: 2013 Oct 22.
Published in final edited form as: Biochim Biophys Acta. 2008 Dec 25;1788(2):507–513. doi: 10.1016/j.bbamem.2008.12.008

Fig. 7.

Fig. 7

(A) The levels of undissolved lipids indicated by the turbidity measurements at 350 nm were monitored over time. It shows that without CHOL in the membrane, 5 mM SDC alone was highly damaging and completely solubilized DLPC lipids within 10 s. The presence of CHOL in the membrane at 30 mol% was unable to protect the DLPC membrane while 50 mol% CHOL display some level of protection. (B) The levels of undissolved lipids indicated by the turbidity measurements at 350 nm were monitored over time. It shows that without CHOL in the membrane, a SDC/UDC combination was mostly as damaging as SDC alone (both at 5 mM). The presence of CHOL in the membrane at 30 or 50 mol% prevented lipids from being solubilized by bile acids, demonstrating the ability of CHOL in the membrane to influence the cytoprotective effect of UDC against SDC attack.