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. Author manuscript; available in PMC: 2014 Mar 15.
Published in final edited form as: ACS Chem Biol. 2012 Dec 27;8(3):513–518. doi: 10.1021/cb3006193

Figure 2.

Figure 2

Changes in the thermodynamic parameters of binding relative to wild-type (WT) protease. The dark blue, magenta and cyan bars are changes in the free energy (ΔΔG), enthalpy (ΔΔH), and entropy (Δ(-TΔS)) of binding, respectively.