Table 5.
Multivariate Analysis Testing the Relationship Between IGFBP-3 With All-Cause Mortality in Older Adults
| Characteristics | HR | 95% CI | p |
|---|---|---|---|
| Model 1* | |||
| IGFBP-3 first quartile (<121.2ng/mL) | — | — | — |
| IGFBP-3 second quartile (121.2–146.6ng/mL) | 0.80 | 0.61–1.05 | .10 |
| IGFBP-3 third quartile (146.6–172.3ng/mL) | 0.69 | 0.52–0.93 | .01 |
| IGFBP-3 fourth quartile (>172.3ng/mL) | 1.43 | 1.03–1.98 | .03 |
| Model 2† | |||
| IGFBP-3 first quartile (<121.2ng/mL) | — | — | — |
| IGFBP-3 second quartile (121.2–146.6ng/mL) | 0.81 | 0.60–1.09 | .17 |
| IGFBP-3 third quartile (146.6–172.3ng/mL) | 0.66 | 0.47–0.93 | .01 |
| IGFBP-3 fourth quartile (>172.3ng/mL) | 1.34 | 0.94–1.90 | .11 |
Notes. IGFBP = insulin-like growth factor-binding protein.
*Model 1: Adjusted for age and sex.
†Model 2: Adjusted for age, sex, caloric intake, GOT, fasting insulin, body mass index, dehydroepiandrosterone sulfate, testosterone, interleukin-6, congestive heart failure, stroke, physical activity, and insulin-like growth factor-1.