Figure 2.

Rotarod performance declines with age. Rotarod performance, the time before falling, is defined as the average time in seconds (s) of three trials. The number of mice per group were 20, 32, and 13 for the adult (6 months, m), old (24 months, m), and elderly mice (>28 months, m), respectively. Values are means (100, 86, and 60) for adult, old, and elderly mice) ± SEM. Results are from a one-way ANOVA (F = 6.3, p = .003) with a Tukey–Kramer Honestly Significant Difference post hoc analysis. *elderly mice significantly different from adult (p = .002) and old mice (p = .037).