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. Author manuscript; available in PMC: 2013 Oct 22.
Published in final edited form as: N Engl J Med. 2012 Dec 13;367(24):2305–2315. doi: 10.1056/NEJMoa1207285

Table 2.

Engraftment in Recipients of Ex Vivo Expanded Cells and MDACC and CIBMTR Controls.

Engraftment Recipients of Ex Vivo
Expanded Cells
(N = 24)
MDACC Controls
(N = 60)
P Value* CIBMTR Controls
(N = 80)
P Value
Neutrophil engraftment
   No. of patients 23 51 67
   Time to engraftment — days
     Median 15 21 0.08 24 <0.001
     Range 9–42 6–45 12–52
   Cumulative incidence — % (95% CI)
     By 26 days 88 (66–96) 62 (48–73) 0.006 53 (41–63) <0.001
     By 42 days 96 (74–99) 83 (71–91) 0.05 78 (67–86) 0.005
Platelet engraftment
   No. of patients 18 38 37
   Time to engraftment — days
     Median 42 41 0.33 49 0.03
     Range 15–62 26–126 18–264
   Cumulative incidence — % (95% CI)
     By 60 days 71 (48–85) 52 (38–63) 0.10 31 (21–41) <0.001
     By 180 days 75 (53–88) 63 (50–74) 0.28 46 (35–58) 0.01
*

P values are for the comparison between recipients of STRO-3+ mesenchymal precursor cells and MDACC controls.

P values are for the comparison between recipients of STRO-3+ mesenchymal precursor cells and CIBMTR controls.