Table 2.
Engraftment | Recipients of Ex Vivo Expanded Cells (N = 24) |
MDACC Controls (N = 60) |
P Value* | CIBMTR Controls (N = 80) |
P Value† |
---|---|---|---|---|---|
Neutrophil engraftment | |||||
No. of patients | 23 | 51 | 67 | ||
Time to engraftment — days | |||||
Median | 15 | 21 | 0.08 | 24 | <0.001 |
Range | 9–42 | 6–45 | 12–52 | ||
Cumulative incidence — % (95% CI) | |||||
By 26 days | 88 (66–96) | 62 (48–73) | 0.006 | 53 (41–63) | <0.001 |
By 42 days | 96 (74–99) | 83 (71–91) | 0.05 | 78 (67–86) | 0.005 |
Platelet engraftment | |||||
No. of patients | 18 | 38 | 37 | ||
Time to engraftment — days | |||||
Median | 42 | 41 | 0.33 | 49 | 0.03 |
Range | 15–62 | 26–126 | 18–264 | ||
Cumulative incidence — % (95% CI) | |||||
By 60 days | 71 (48–85) | 52 (38–63) | 0.10 | 31 (21–41) | <0.001 |
By 180 days | 75 (53–88) | 63 (50–74) | 0.28 | 46 (35–58) | 0.01 |
P values are for the comparison between recipients of STRO-3+ mesenchymal precursor cells and MDACC controls.
P values are for the comparison between recipients of STRO-3+ mesenchymal precursor cells and CIBMTR controls.