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. Author manuscript; available in PMC: 2014 Jul 15.
Published in final edited form as: Cancer Res. 2013 May 30;73(14):4439–4450. doi: 10.1158/0008-5472.CAN-13-0187

Figure 2.

Figure 2

Effect of hSGZ treatment on MCF-7 and MCF-7/HER2 cells. A, parental MCF-7 cells and MCF-7 cells that stably overexpress HER2 (MCF-7/HER2) were analyzed for Fn14 cell surface expression by flow cytometry. B, cytotoxic effects of rGel, ITEM4-rGel and hSGZ were analyzed on MCF-7 and MCF-7/HER2 cells. Student’s t test was used to calculate statistical significance. Data are representative of three independent experiments. C and D, MCF-7 and MCF-7/HER2 cells were treated with indicated concentration of hSGZ for 48 h and whole cell lysates were analyzed by Western blot with the indicated antibodies.